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A small increase in serum creatinine was reported in patients with moderate renal insufficiency treated with Januvia relative to those on placebo

Miyashita, K., Endo, S., Uto, A., Inoue, H., Fujii, K., Ryuzaki, M., Kinouchi, K., & Itoh, H

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GLP1-S Research Applications (Benefits) GLP1-S has become a central focus of preclinical and non-clinical investigations due to its wide-ranging influence on metabolism, appetite, and endocrine pathways